Myelomonocytic Antigen L1

《英文msh詞典》Myelomonocytic Antigen L1
[入口詞] Myelomonocytic Antigen L1
[主題詞] Leukocyte L1 Antigen Complex
[英文釋義] A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious,inflammatory,and malignant disorders,including rheumatoid arthritis,inflammatory bowel disease,and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif,and has been shown to possess antimicrobial activity.